I'll admit, I'm biased, as I really don't think (want to) believe he was doping....but I found this on Landis' Wikipedia profile. Interesting, he was using Cortisone (and had approval for it) and has hypothyroidism which can cause testosterone to get out of whack. (A family member has this, and I can definitely attest it's true.)
On July 27
the Phonak Cycling Team announced that Landis tested positive in a drug test given to him after Stage 17. He tested positive for an abnormally high ratio of the hormone testosterone
during Stage 17 of the race. On the same day the allegations were made public, Landis denied doping
in order to win the 2006 Tour de France.
Landis has been suspended pending the submission and results of a second test or "B sample." His team has stated he will be fired from the team should his B sample prove positive.
The exact T/E ratio measured for Landis has not been made public, and there is some debate as to whether the test necessarily proves doping.
In particular, hypothyroidism
, which Landis has, causes low levels of SHBG
, which in turn can cause relatively high levels of testosterone
(since testosterone must bind with SHBG before it can be biologically processed out of the system). The net result is an accumulation of testosterone and an abnormally high T/E ratio. Even though he is on medication for his hypothyroidism, thyroid levels are notoriously unstable in those with hypothyroidism, even if taking medication[citation needed