Bill - Good luck with whatever you decide to do.
If I'm understanding you correctly, this move would allow your wife to stay at home and raise your Kid(s)? Without taking a financial hit? *That's a powerful argument for doing it. My wife gave up teaching to raise our three kids, and they'll forever thank her. It was a huge factor in their confidence, academic success, creativity, and current world view / values.
We ate it financially, and I worked 12 hour days in retail and manufacturing. In a sense, I never got many two week periods in which the sh!t wasn't hitting the fan to be with them in a more concentrated way. So I had to grab every opportunity I could, and guess what? It all worked out.
Would your taking this position qualify or enable you to take a better career path with less travel and more flexibility in a couple of years? *
And as far as your customers and employees, you could either sell your shop to one of them or, as HD says, fuggedaboudit. When I sold off and closed my retail stores, my 'partner' of ten years to whom I had given equity basically disappeared after I gave her the recommendation that got her next job. Life goes on.